Storage Stability

The increasing complexity of registration requirements has added considerably to administrative burdens placed on study sponsors, particularly when the implications of GLP are taken into account. We offer complete formulation packages using CIPAC tests to PSD guidelines. We also offer accelerated and long-term storage studies for registration of pesticides. Analytical programmes of Oxford Analytical Ltd follow recognised registration guidelines, generally following CIPAC and EEC methodology. Where these are not available, standard in-house procedures are followed.

We provide interpretation of the results and comparison with the PSD registration guidelines. If we do find a result which is outside a specified range, it is our policy to contact the client immediately whereupon the testing may be suspended, thereby avoiding any additional charges. The range of tests employed is extensive and all tests are conducted by the staff of Oxford Analytical Ltd to the requirements of GLP.

We have also developed an in-house procedure to conduct assays on the effectiveness of cleaning procedures. This is now a registration requirement and our methodology can be adapted to cover your company’s recommended cleaning procedure.

Shown below are just a few of the CIPAC and EEC tests that we can undertake.

*Active Ingredient Determination
(using HPLC, LCMS and GCMS)

*Appearance and physical state

*Explosive properties (EEC A14)

*Oxidising properties (EEC A17, solids)

*Flashpoint and other indications of
flammability (EEC A9 to A16)

*Acidity / alkalinity (CIPAC MT 31)

*pH determination (CIPAC MT 75)

*Viscosity (OECD method 114)

*Surface tension (EEC A5)

*Relative density (EEC A3)

*Storage stability (accelerated testing at
temperatures between 30 and 54°C)

*Storage stability (ambient testing over
2 years)

*Storage stability (cold stability testing at
0°C or lower)

*Wettability (CIPAC MT 53.3)

*Persistent foaming (CIPAC MT 47.2)

*Suspensibility (CIPAC MT 15.1 and 168)

*Spontaneity of dispersion
(CIPAC MT 160 and 174)

*Dilution stability (CIPAC MT 41)

*Dry sieve test (CIPAC MT 59.1 and 59.2)

*Wet sieve test (CIPAC MT 59.3 and 167)

*Particle size distribution
(CIPAC MT 58.2 and 170)

*Content of dust/fines (CIPAC MT 171)

*Attrition and friability (CIPAC MT 178)

*Emulsifiability, re-emulsifiability and
emulsion stability, dispersion stability
(CIPAC MT 36.1, 36.2, 173, 20 and 180)

*Flowability (CIPAC MT 172)

*Pourability (CIPAC MT 148)

*Dustability


*Explosivity certificates can also be
produced from theoretical modelling of
the chemicals in formulation.